| ORIGINAL ARTICLE | |
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Ionic liquid catalyzed multicomponent synthesis of 3,4-dihydro-3-substituted-2H-naphtho[2,1-e][1,3]oxazine derivatives Amol H. Kategaonkar, Swapnil S. Sonar, Kiran F. Shelke, Bapurao B. Shingate and Murlidhar S. Shingare Org. Commun. (2010), 3:1; 1-7 Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431 004, (MS), India Abstract:An efficient and novel one-pot synthesis of 3,4-dihydro-3-substituted-2H-naphtho[2,1-e][1,3]oxazine derivatives from 1-naphthol, various anilines and formalin at room temperature stirring. The six-membered N,O-heterocyclic skeleton was constructed via 1-benzyl-3-methyl imidazolium hydrogen sulphate [bnmim] [HSO4] promoted Mannich type reaction. Keywords : 1,3-oxazines; ionic liquid; Mannich type reaction; multicomponent reaction. |