12.

Flavonol 3-O-Glycosides from Three Algerian Bupleurum Species

Reguia Bencheraiet, Ahmed Kabouche, Zahia Kabouche, Rachid Touzani and Maurice Jay

Laboratoire d’Obtention de Substances Thérapeutiques, Université Mentouri-Constantine, 25000 Constantine, Algérie

Université Mohamed Premier, Oujda LCAE-URAC 18; COSTE; Faculté des Sciences, Oujda & Faculté Pluridisciplinaire Nador, Morocco

Laboratoire de biologie moléculaire et phytochimie, Université Claude Bernard , Lyon, France

Abstract: Flavonoids distribution in three algerian Bupleureum (Apiaceae) species has been investigated. Quercetin (1), quercetin 3-rutinoside (2) and isorhamnetin 3-rutinoside (3) were found in the endemic species B. plantagineum Desf. Three kaempferol glycosides, kaempferol 3-glucoside (4), kaempferol 3-galactoside (5), kaempferol 3-rutinoside (6) and three quercetin glycosides, quercetin 3-rutinoside (2), quercetin 3-glucoside (7) and quercetin 3-galactoside (8), have been isolated from B. fruticosum L. while isorhamnetin (9), isorhamnetin 3-galactoside (10) and isorhamnetin 3-galactorhamnoside (11) were found in B. spinosum L. Seven flavonols are reported here for the first time from the genus.

Keywords: Bupleurum ; B. plantagineum ; B. fructicosum ; B. spinosum ; flavonoids .