Records of Natural Products

Year: 2016  Volume: 10  Issue: 1




Determination of Antioxidant, Anticholinesterase, Tyrosinase Inhibitory Activities and Fatty Acid Profiles of 10 Anatolian Klasea Cass. Species

Gülsen Tel, Bekir Doğan, Ebru Erol, Mehmet Öztürk, Said Nadeem, Zain Ullah, Mehmet Emin Duru and Ahmet Duran

Muğla Sıtkı Koçman University, Faculty of Science, Department of Chemistry, 48121 Kötekli, Muğla Türkiye

Necmettin Erbakan University, Faculty of Ahmet Keleşoğlu Education, Division of Science Education, Meram, Konya, Türkiye

Selçuk University, Faculty of Science, Department of Biology, Selçuklu, Konya, Türkiye

Abstract: In search of new natural fatty acid sources, extract of 10 different Turkish Klasea species were studies. Fatty acids of Klasea species were studied by GC and GC-MSD. Oleic acid (4.8-45.8%), palmitic acid (15.6-51.8%), linoleic acid (0.3-45.5%), palmitoleic acid (0.8-28.4%) and linolenic acid (15.6-34.6%) were the main fatty acids elucidated. All extracts were also subjected to acetylcholinesterase, butyrylcholinesterase, tyrosinase, β-carotene-linoleic acid, DPPH • scavenging, CUPRAC and ferrous ion-chelating ability activities. Total flavonoid and phenolic contents were determined as quercetin and pyrocatechol equivalents. All extracts showed significant antioxidant activity in all tests, except hexane extracts of K. serratuloides and K. cerinthifolia that showed weak inhibition against BChE and AChE. The hexane extract of K. coriaceae and methanol extract of K. serratuloides exhibited notable tyrosinase inhibitory activity.

Keywords: Klasea species; tyrosinase inhibitory activity; anticholinesterase activity; antioxidant activity; phenolic and flavonoid contents; fatty acid s. © 2015 ACG Publications. All rights reserved.