Investigation of Insect Repellent Activity of Cyclocolorenone Obtained from the Red Alga Laurencia intricata
Takahiro Ishii, Yuto Shinjo, Miyu Miyagi, Hiroshi Matsuura, Tsuyoshi Abe, Norio Kikuchi and Minoru Suzuki
Department of Bioscience and Biotechnology, Faculty of Agriculture, University of the Ryukyus, Senbaru 1, Nishihara, Okinawa 903-0213, Japan
Department of Materials Chemistry, National Institute of Technology, Asahikawa College, 2-2-1-6 Shunkodai, Asahikawa 071-8142, Japan
The Hokkaido University Museum, Hokkaido University, Sapporo 060-0810, Japan
Coastal Branch of Natural History Museum and Institute, Chiba, 123 Yoshio, Katsuura, Chiba 299-5242, Japan
Abstract: Three known secondary metabolites were isolated from the organic extract of Laurencia intricata. Their structures were identified by NMR and MS experiments and comparison with the literature data. An aromadendrane sesquiterpene, (+)-cyclocolorenone showed strong repellent activity against the maize weevil Sitophilus zeamais Motschulsky (Coleoptera: Curculionidae) adults. It had the same activity as natural insecticides, pyrethrins, with a ED 50 value of 2.0 m g/cm 2. This is the first report of insect repellent activity of (+)-cyclocolorenone. The results suggest that the red alga Laurencia is a promising source of bioactive compounds which can be used as potential biocontrol agents for stored-product insects.
Keywords: Cyclocolorenone; insect repellent activity; Sitophilus zeamais; Laurencia intricata . © 2018 ACG Publications. All rights reserved.