A facile one-pot synthesis of 3-(1-Benzyl-2-phenyl-1H-imidazol-4-yl)-4-hydroxy-6-methyl-2H-pyran-2-one derivatives via multi-component approach
Thirupaiah Bade and Rajeswar Rao Vedula
Department of Chemistry, National Institute of Technology, Warangal-506004, A.P., India
Abstract: A one pot, four component synthesis of 1, 2, 4-trisubstituted imidazoles is described by reacting a mixture of bromo dehydroacetic acid, aromatic aldehyde, benzyl amine, and ammonium acetate in dry alcohol. All the synthesized compounds were characterized by their analytical and spectral data.
Keywords: bromo dehydroacetic acid; aromatic aldehyde; benzyl amine; ammonium acetate; imidazole; one-pot; multi component reactions. © 2014 ACG Publications. All rights reserved. |