Microwave induced synthesis of bis-Schiff bases from propane-1, 3-diamine as promising antimicrobial analogs
Avinash Shinde, Sainath Zangade, Shivaji Chavan and Yeshwant Vibhute
Department of Chemistry, N.E.S. Science College, Nanded (MS) India-431605
Organic research center, Department of Chemistry Yeshwant Mahavidyalaya, Nanded (MS) India-431602
Abstract: 1,3-Diamine 1 on condensation with different halogeno substituted benzaldehydes 2a-p under microwave irradiation affords novel series of bis-schiff bases 3a-p. Structures of the newly synthesized bis-Schiff bases established on the basis of spectroscopic data. Further, all compounds screened for antimicrobial activity against Staphylococus aureus, Escherchia coli, Aspergillus niger and Aspergillus flavus. Most of the titles compounds show potent activity.
Keywords: 1,3-Diamine; bis-schiff bases; microwave irradiation; microbial activity. © 2014 ACG Publications. All rights reserved. |