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Triterpenoids from Garcinia rigida

Berna Elya, Hong Ping He, Soleh Kosela, Muhammad Hanafi and Xiao Jiang Hao

Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, China

Department of Pharmacy, Universitas Indonesia, Kampus UI Depok, 16424, Indonesia

Indonesian Science Institute-LIPI, Indonesia

Abstract: The leaves of Garcinia rigida afforded six triterpenoid compounds, friedelin (1), lanosta-8,25-en-3 b -ol (2), stigmasterol (3), lupeol (4), 3 b -hydroxy-20(29)-en-lupan-30-al (5) and 3 b -hydroxy-20(29)-en-lupan-30-ol (6). The structures of 1-6 were elucidated by IR, MS, NMR spectroscopies and comparison of their spectroscopic data with those reported in the literatures. Compound 6 showed toxicity to Artemia salina in brine shrimp lethality test (BLST) with LC 50 27.72 µg/mL.

Keywords: Garcinia rigida ; triterpenoid; brine shrimp lethality test (BLST).