15.

Pandanusphenol A and B: Two New Phenolic Compounds from the Fruits of Pandanus tectorius Soland

Xiaopo Zhang, Haifeng Wu, Chongming Wu, Peng Guo, Xudong Xu and Meihua Yang

Institute of Medicinal Plant DevelopmentChinese Academy of Medicinal Sciences& Peking Union Medicinal Collece, Beijing 100094, China, College of Pharmaceutical Sciences , Hainan Medicinal University , Haikou , 571101 China

Abstract: Two new phenolic compounds, P andanusphenol A (1) and B (2) , were obtained from the fruits of Pandanus tectorius . The ir structures including absolute configurations were determined by extensive spectroscopic analysis including 2D NMR experiments ( 1H- 1H COSY, HMBC , and NOESY ) and HRESIMS results as well as CD data . The substituted pattern of two methoxy group s on the phenyl ring of Pandanusphenol A (1) is rarely seen in natural furofuran lignans .

Keywords: Pandanus tectorius ; P andanusphenol A ; P andanusphenol B .