5.

Isolation and Characterization of New Constituents from Tricholepis eburnea

Shagufta Rasool, Noureen Khan, Rashad Mehmood and Farzana Shaheen

H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan

Department of Chemistry, Sarhad University of Science and Information Technology, Peshawar, Pakistan

Department of Chemistry, Sardar Bahadur Khan Womenʹs University, Quetta, Pakistan,

Department of Chemistry, Hazara University Mansehra-21120, Pakistan

Abstract: Through current phytochemical investigation on dichloromethane (DCM) fraction of 80% methanolic extract of Tricholepis eburnea, seven chemical constituents were isolated and their structures were elucidated by spectroscopic analyses. Two of them were identified as new flavonoids as trichonoide A (1) and trichonoide B (2), while the other five known constituents β-sitosterol (3), 3-O-acetyl-β-stigmastanol (4), 3β,17β,20-trihydroxy-l-oxo-(20R, 22 R)- witha-5,14,24-trienolide (5), pectolinaringenin (6), and dillenetin (7) were isolated for the first time from this species .