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An improved process for eszopiclone: Anti-insomnia agent

Original Article

JOURNAL 139

Organic Communications
VOLUME & ISSUE
Year: 2008 Issue: 2 April-June
PAGES
p.33 - 38
STATISTICS
Viewed 2016 times.
AUTHORS
    Kandala S. Charyulu, Chinta R. Reddy, Kisara Satyanarayana, Mandava V. N. B. Rao, V.V.N.K. Prasad Raju, Adla V. Kumar, Virumudi H. Bindu, Vijayavitthal T. Mathod, Apurba Bhattacharyaand Rakeshwar Bandichhor,
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GRAPHICAL ABSTRACT

ABSTRACT

Application of stable hydrochloride salt of 1-chlorocarbonyl-4-methylpiperzine 2 and tetrabutyl ammonium bromide (TBAB) as a phase transfer catalyst in an improved process of eszopiclone 1 is presented.

 KEYWORDS
  • Zopiclone
  • phase transfer catalyst
  • resolution