JOURNAL 178


Organic Communications
VOLUME & ISSUE
Year: 2012 Issue: 1 January-March
PAGES
p.1 - 11
STATISTICS
Viewed 1912 times.
AUTHORS
    K. L. Ameta , Biresh Kumar, Nitu S. Rathore and B. L. Verma
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GRAPHICAL ABSTRACT


ABSTRACT


Various 4'-hydroxy-3',5'-dinitro substituted chalcones 1 and S-benzylthiouronium chloride (SBT) 2 in the presence of DMF-organic bases (morpholine/ pyrrolidine/ piperidine) gave 4,6-diaryl-2-(4-morpholinyl / 1-pyrrolidinyl /1-piperidinyl)- pyrimidines 4, 5and 6 in a facile one-pot conversion. In an another attempt reactants 1 and 2 yielded intermediate 2-benzylthiopyrimidines 3, in presence of DMF, which on treatment with heterocyclic secondary amines gave products 4, 5 and 6 in an alternate two-step process.

KEYWORDS
  • Chalcone
  • S-benzylthiouronium chloride
  • heterocyclic secondary amines.