JOURNAL 789


Organic Communications
VOLUME & ISSUE
Year: 2016 Issue: 4 October-December
PAGES
p.94 - 101
STATISTICS
Viewed 1948 times.
AUTHORS
    Mavallur Varalakshmi and Chamarthi Nagaraju
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


Synthesis of a series of new N -4-(N-2-(trifluoromethylphenyl))sulfamoyl amide derivatives 6(a-i) was accomplished by a sequence of reactions by using aniline as a starting compound (1). The newly synthesized compounds were characterized by the spectral analysis and evaluated their antibacterial activity. 5-Nitro-N-(4-(N-(2-(trifluoromethyl)phenyl)sulfamoyl)phenyl)furan-2-carboxamide (6b) exhibited the highest activity.

KEYWORDS
  • Aniline
  • trifluoroacetic anhydride
  • sulfonylchloride
  • antibacterial activity

SUPPORTING INFORMATION


Supporting Information
Download File 11-OC-1609-436_SI.pdf (226.99 KB)