JOURNAL 1468


Organic Communications
VOLUME & ISSUE
Year: 2019 Issue: 4 October-December
PAGES
p.217 - 221
STATISTICS
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AUTHORS
  • Dmytro Kravtsov
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


In this study, some benzoyl substituted fused quinazolines derivatives 4a-d were synthesized using Fieser’s reagent. Also this work reports about two non-specific products 5a and 6 of the reaction which were isolated from the reaction mixture. Based on the experimental data the potential oxidation mechanism of ketone 4a by chromium trioxide was described. The synthesized compounds were characterized by 1H, 13C, 19F NMR and LC-MS data.

KEYWORDS
  • oxidation
  • fused quinazolines derivatives
  • Fieser’s reagent
  • benzyl to benzoyl
  • mechanism

SUPPORTING INFORMATION


Supporting Information
Download File A5-70-OC-1911-1468-SI.pdf (5.18 MB)