Waste to wealth: agro-waste catalyzed green method synthesis of 5-aryl-1,2,4-triazolidine-3-thiones and 1,2,4-triazospiro-3-thiones

Original Article

JOURNAL 2040

Organic Communications

VOLUME & ISSUE

Year: 2021 Issue: 3 July-September

PAGES

p.240 - 254

DOI ADDRESS

http://doi.org/10.25135/acg.oc.107.21.04.2040

STATISTICS

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AUTHORS

Santosh Y. Khatavi
Kantharaju Kamanna

GRAPHICAL ABSTRACT

ABSTRACT

TThis paper describes novel agro-waste derived Water Extract of Orange Fruit Shell Ash (WEOFSA) catalyzed synthesis of 5-aryl-1,2,4-triazolidine-3-thiones and 1,2,4-triazospiro-3-thiones under microwave irradiation. Herein, we have developed inexpensive, facile and green method synthesis of cyclic thiones by the reaction of aromatic aldehyde and cyclic ketone, with thiosemicarbazide in presence of agro-waste derived catalyst. The obtained product is chromatographically pure after recrystallization from ethanol, and final product is characterized by various spectroscopic techniques FT-IR, 1H-, 13C-NMR and HR-MS.

KEYWORDS

Agro-waste
green method
cyclic ketone
semicarbazide
microwave

SUPPORTING INFORMATION

Supporting Information

Download File A3-107-OC-2104-2040-SI.pdf (865.27 KB)