Green methods for the synthesis of chalcones: An overview with appraisal to sustainable development and bioactive compounds

Review Article

JOURNAL 3495

Organic Communications

VOLUME & ISSUE

Year: 2025 Issue: 2 April-June

PAGES

p.38 - 59

DOI ADDRESS

http://doi.org/10.25135/acg.oc.189.2504.3495

STATISTICS

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AUTHORS

Vikas Borge
Satish Manjare
Bhushan B. Popatkar

GRAPHICAL ABSTRACT

ABSTRACT

In recent years, there has been a growing interest in developing green and sustainable synthetic strategies for chalcones, aiming to minimize waste, reduce the use of hazardous chemicals, and enhance the overall efficiency of the reactions. This review provides an overview of various green synthesis approaches for chalcones and their derivatives, emphasizing environmentally friendly techniques such as solvent-free reactions, microwave-assisted synthesis, ultrasound-assisted synthesis, and enzyme-catalytic methods. Additionally, the biological activities of chalcones synthesized via green methods are explored, underscoring their potential in drug development and therapeutic applications

KEYWORDS

Chalcones
green synthesis
biologically active compounds