JOURNAL 402


Records of Natural Products
VOLUME & ISSUE
Year: 2011 Issue: 2 April-June
PAGES
p.92 - 99
STATISTICS
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AUTHORS
    Andrea Maxia, Maria A. Frau, Bruno Marongiu, Alessandra Piras, Silvia Porcedda, Danilo Falconieri, Maria J. Gonçalves, Carlos Cavaleiro and Ligia Salgueiro
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GRAPHICAL ABSTRACT


ABSTRACT


The composition of supercritical CO 2 extracts and essential oils obtained by hydrodistillation of Bupleurum fruticosum L., growing spontaneously in Italy and Portugal, and its antifungal activity is reported. The collected extracts were analyzed by GC-FID and GC-MS methods. The minimal inhibitory concentration (MIC) and the minimal lethal concentration (MLC) were used to evaluate the antifungal activity of the oils against Candida albicansC. tropicalisC. kruseiC. guillermondiiC. parapsilosisCryptococcus neoformansTrichophyton rubrumT. mentagrophytesMicrosporum canisM. gypseumEpidermophyton floccosumAspergillus nigerA. fumigatus and A. flavus.

KEYWORDS
  • Bupleurum fruticosum L.
  • essential oil
  • supercritical carbon dioxide
  • antifungal activity.