JOURNAL 413


Records of Natural Products
VOLUME & ISSUE
Year: 2011 Issue: 3 July-September
PAGES
p.158 - 175
STATISTICS
Viewed 1917 times.
AUTHORS
    İlhami Gülçin, Fevzi Topal, S. Beyza Öztürk Sarıkaya, Ercan Bursal, Gökhan Bilsel and Ahmet C. Gören
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


Medlar is the fruit of Mespilus germanica L. in the family of Rosaceae. The present study outlines that the native medlar (Mespilus germanica L.) fruits an extremely rich source of antioxidants. In this study, antioxidant and antiradical property of medlar fruits were evaluated. Total phenolics and flavonoids amounts in lyophilized extract of medlar (LEM) fruits were calculated as gallic acid and quercetin equivalents, respectively. Antioxidant and radical scavenging activity of LEM were investigated using different in vitro assays including 1,1-diphenyl-2-picryl-hydrazyl (DPPH∙), N,N-dimethyl-p-phenylenediamine (DMPD •+), and superoxide anion radicals (O 2 •-) scavenging activity, hydrogen peroxide (H 2O 2), ferric ions (Fe 3+) and cupric ions (Cu 2+) reducing ability, Fe 3+-TPTZ reducing ability, ferrous ions (Fe 2+) chelating activity as trolox equivalent. In addition, quantitative amounts of caffeic acid, ferulic acid, syringic acid, ellagic acid, quercetin, α-tocopherol, pyrogallol, p-hydroxybenzoic acid, vanillin, p-coumaric acid, gallic acid and ascorbic acid in LEM were detected by high performance liquid chromatography and tandem mass spectrometry (LC-MS/MS). The presence of these antioxidant compounds can be considered as a quality parameter for edible medlar fruits.

KEYWORDS
  • Medlar
  • Mespilus germanica
  • antioxidant activity
  • radical scavenging
  • trolox equivalent