JOURNAL 442


Records of Natural Products
VOLUME & ISSUE
Year: 2012 Issue: 1 January-March
PAGES
p.35 - 48
STATISTICS
Viewed 1204 times.
AUTHORS
    Sílvia M. Albano, A. Sofia Lima, M. Graça Miguel Luis G. Pedro, José G. Barroso and A. Cristina Figueiredo
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


The scavenging of free radicals and superoxide anion, the inhibition of 5-lipoxygenase and the antiacetylcholinesterase activities of essential oils and decoction waters of eight aromatic plants (Dittrichia viscosa , Foeniculum vulgareOriganum vulgareSalvia officinalisThymbra capitata , Thymus camphoratusThymus carnosus and Thymus mastichina) were studied. The essential oils were dominated by 1,8-cineole in S. officinalis (59%), T. mastichina(49%) and T. camphoratus (21%); borneol (20%) in T. carnosus; carvacrol in Thymbra capitata (68%); γ -terpinene (49%) in O. vulgare; α -pinene (26%) in F. vulgare; and trans-nerolidol (8%) +  β -oplopenone (7%) in D. viscosaO. vulgare decoction waters had the highest amount of phenols (4 5 ± 3 mg GAE/mL) while F. vulgare only had 5 ± 0 mg GAE/mL. The decoction waters showed higher radical scavenging activity than the essential oils. O. vulgare decoction water showed the best antioxidant activity (IC 50= 3 ± 0  m g/mL), while the most effective essential oils were those of Thymbra capitata(IC 50=61 ± 2  m g/mL) and O. vulgare (IC 50=15 6 ± 5  m g/mL). Thymbra capitata (IC 50= 6 ± 0  m g/mL) decoction water showed the best superoxide anion scavenging activity. F. vulgare decoction water and essential oil revealed the best 5-lipoxygenase inhibition capacity (IC 50=2 7 ± 1  m g/mL and IC 50=6 8 ± 2  m g/mL, respectively). T. mastichina (IC 50=4 6 ± 4  m g/mL), S. officinalis (IC 50=5 1 ± 4  m g/mL), Thymbra capitata (IC 50=5 2 ± 1  m g/mL) and T. camphoratus (IC 50=13 7 ± 2  m g/mL) essential oils showed the best antiacetylcholinesterase activity.

KEYWORDS
  • Essential oils
  • decoction water
  • biological activities
  • Apiaceae
  • Asteraceae
  • Lamiaceae.