JOURNAL 639


Records of Natural Products
VOLUME & ISSUE
Year: 2012 Issue: 2 April-June
PAGES
p.175 - 179
STATISTICS
Viewed 1904 times.
AUTHORS
    Mehmet Emin Duru, Gülsen Tel, Mehmet Öztürk and Mansur Harmandar
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GRAPHICAL ABSTRACT


ABSTRACT


 The essential oil from the aerial parts of Salvia chrysophylla Staph (Lamiaceae), endemic to Turkey, was investigated by using GC and GC-MS. Fifty-four of 55 components, represented 99.52% of the total oil, were identified. The major components of the essential oil were found to be α-terpinenyl acetate (36.31%), β-caryophyllene (15.29%), linalool (8.12%) and β-elemene (4.26%). The antioxidant activity of the oil was investigated by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and β-carotene/linoleic acid tests. Anticholinesterase activity was screened against acetylcholinesterase and butyrylcholinesterase which are the chief enzymes of Alzheimer’s disease. The essential oil showed weak antioxidant activity. However, at 1 mg/mL concentration, the essential oil exhibited mild acetylcholinesterase (52.5±2.0%) and moderate butyrylcholinesterase (76.5±2.7%) inhibitory activity.

KEYWORDS
  • Salvia chrysophylla
  • essential oil
  • GC and GC-MS
  • antioxidant activity
  • anticholinesterase activity