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The New Alkaloids from Antidesma cuspidatum M.A.

JOURNAL 755

Records of Natural Products
VOLUME & ISSUE
Year: 2014 Issue: 4 October-December
PAGES
p.342 - 347
STATISTICS
Viewed 3221 times.
AUTHORS
    Berna Elya, Roshamur C. Forestrania, Mat Ropi, Soleh Kosela, Khalijah Awang, Hanita Omar and A. Hamid A. Hadi
PDF OF ARTICLE

GRAPHICAL ABSTRACT

ABSTRACT

Two new alkaloids, cuspidatin (1) and cuspidatinol (2), were isolated from Antidesma cuspidatum M.A. (Euphorbiaceae). The structures were determined by means of spectroscopic analysis (IR, MS, and NMR spectroscopy). The results of cytotoxicity evaluation showed that compounds 1 and 2 were inhibitory to L1210 cells, with IC 50 values 8.41 and 6.36 µg/mL respectively.

 KEYWORDS
  • Antidesma cuspidatum M.A.
  • Alkaloids
  • Euphorbiaceae
  • Cytotoxic activity. © 2014 ACG Publications. All rights reserved.

SUPPORTING INFORMATION

Supporting Information
Download File 48-RNP-1310-448_SI.pdf (2.61 MB)