JOURNAL 561


Records of Natural Products
VOLUME & ISSUE
Year: 2015 Issue: 3 July-September
PAGES
p.441 - 445
STATISTICS
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AUTHORS
    Luis Enrique Cuca-Suarez, Franco Della-Monache and Ericsson Coy-Barrera
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GRAPHICAL ABSTRACT


ABSTRACT


From leaves and bark of Amyris pinnata Kunth twelve compounds were isolated, corresponding to six lignans 1-6, three coumarins 7-9, a sesquiterpene 10, an oxazole alkaloid 11, and a prenylated flavonoid 12,. Metabolites were identified by spectroscopic techniques ( 1H and 13C NMR, EIMS) and by comparison with published data in the literature. C ytotoxicity against leukemia, solid tumors, and normal cells was evaluated for all isolated compounds. Lignans were found to be the most cytotoxic compounds occurring in A. pinnata.

KEYWORDS
  • Amyris pinnata
  • lignans
  • coumarins
  • alkaloid
  • flavonoid
  • cytotoxicity