JOURNAL 338


Records of Natural Products
VOLUME & ISSUE
Year: 2016 Issue: 1 January-February
PAGES
p.40 - 46
STATISTICS
Viewed 1108 times.
AUTHORS
    N Manika, Chandan Singh Chanotiya, Mahendra Darokar, Subhash Singh and Guru Das Bagchi
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GRAPHICAL ABSTRACT


ABSTRACT


Chemical and biological investigations were carried out to evaluate the composition and anti-microbial potential of a rare Artemisia species viz. Artemisia stricta Edgew. f. stricta Pamp. essential oil for the first time. GC and GC/MS analysis resulted in the identification of 27 compounds, which constituted 93.2% volatile constituents of the oil. The major constituents were capillene (41.6%), spathulenol (14.6%) and β-caryophyllene (13.4%). The oil was also assayed to determine its antimicrobial potential against eight bacterial and six fungal strains. The oil exhibited both antifungal and antibacterial activities. Among bacteria, the oil was most effective against Staphylococcus epidermidis (MIC 0.625 mg/mL ) followed by Staphylococcu. Aureus (MIC 1.25 mg/mL ). While among fungi, the oil was most effective against Aspergillus flavus followed by Aspergillus niger and Sporothrix schenckii with MIC as low as 0.625 mg/mL.

KEYWORDS
  • Artemisia stricta
  • Asteraceae
  • Essential oil
  • Capillene
  • Antimicrobial activity.