JOURNAL 248


Records of Natural Products
VOLUME & ISSUE
Year: 2017 Issue: 3 May-June
PAGES
p.290 - 298
STATISTICS
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AUTHORS
    Ibrahim Halil Gecibesler, Ibrahim Demirtas, Lutfi Behcet and Ali Riza Tufekci
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


Two new flavonoidsnamely 7,5′-dimethoxyisoetin (1) and homoorientin-6′′-4-O-methyl-myo-inositol (2) together with six known compounds were isolated and identified as isoorientin (3), genkwanin(4), dihydrokaempferol,7,4′-dimethylether (5), eriodictyol 7,4′-dimethylether (6), D-(+)-pinitol (7) and 3-O-β-D-glucopyranosyl spinasterol (8) from the aerial parts of endemic Phryna ortegioides for the first time. Their chemical structures were determined by 1D ( 1H, 13C and DEPT) and 2D (COSY, HSQC, ROESY, NOESY, TOCSY and HMBC) NMR and mass spectrometry. The antioxidant properties of pure secondary metabolites were analyzed on the basis of ferric thiocyanate method. Compound 1 displayed the highest antioxidant activity with an inhibition rate of 98.09% at a concentration of 100 µg/mL.

KEYWORDS
  • Phryna ortegioides
  • antioxidant activity
  • caryophyllaceae
  • flavone
  • inositol.

SUPPORTING INFORMATION


Supporting Information
Download File 35-RNP-1607-464-SI.pdf (835.04 KB)