JOURNAL 857


Records of Natural Products
VOLUME & ISSUE
Year: 2019 Issue: 1 January-February
PAGES
p.91 - 95
STATISTICS
Viewed 1641 times.
AUTHORS
    Ling-Jing Mao , Xiao-Yu Xie, Yang Gao , Peng-Xiang Lai and Qing-lin Ma
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


This study investigated the chemical composition and in vitro antibacterial and antioxidant activities of the essential oil obtained by hydrodistillation from the aerial parts ofLeonurus pseudomacranthus Kitag for the first time. The chemical composition was studied by GC-FID and GC-MS. Forty-nine compounds accounting for 91.1% of the essential oil were identified. The major components were s clareol (34.8%), β- c aryophyllene (7.1%), p recocene (I) (6.3%) and α- m uurolene (5.3%). The antibacterial activity of the essential oil was assessed by the disc diffusion and microdilution methods. The essential oil showed excellent antibacterial activity against Bacillus subtilis and Staphylococcus aureus with MIC values of 0.039 mg/mL and 0.156 mg/mL, respectively. Moreover, the antioxidant potential was evaluated by DPPH, ABTS and FRAP assays. The essential oil gave IC 50 values of 1.5 13 mg/mL, 0.1 52 mg/mL in DPPH and ABTS methods, and a Trolox equivalent concentration of 33.63 μmol Trolox × g -1 in FRAP method. The results indicated that the essential oil could be regarded as a promising product for pharmaceutical and food industry after more detailed study.

KEYWORDS
  • Leonurus pseudomacranthus Kitag
  • essential oil
  • antibacterial activity
  • antioxidant activity.

SUPPORTING INFORMATION


Supporting Information
Download File 83-RNP-EO_1803-98-SI.pdf (687.23 KB)