JOURNAL 804


Records of Natural Products
VOLUME & ISSUE
Year: 2019 Issue: 1 January-February
PAGES
p.18 - 23
STATISTICS
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AUTHORS
    Farukh S. Sharopov, Payrav D. Khalifaev, Prabodh Satyal, Yanfang Sun, Abduahad Safomuddin, Safol Musozoda, Michael Wink and William N. Setzer
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


The underground parts of Ferula  tadshikorum M. Pimenwere collected from the southern part of Tajikistan. The essential oils were obtained by hydrodistillation and analyzed by GLC-FID and GLC-MS. A total of 26 compounds were identified representing 94.4 % of total oil composition. The essential oil was dominated by the sulfur-containing compounds (Z)-1-propenyl sec-butyl disulfide (37. 3%), (E)-1-propenyl sec-butyl disulfide (29.9%), (E)-1-propenyl 1-(methylthio)propyl disulfide (16.8%), and propyl sec-butyl disulfide (4.8%). The antioxidant, antimicrobial and cytotoxic activities of the essential oil was evaluated. To our best knowledge, this is the first report concerning the chemical composition and biological activity of the essential oil obtained from the underground parts of F.  tadshikorum.

KEYWORDS
  • Ferula tadshikorum
  • essential oil composition
  • disulfides