JOURNAL 1257


Records of Natural Products
VOLUME & ISSUE
Year: 2020 Issue: 1 January-February
PAGES
p.57 - 64
STATISTICS
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AUTHORS
  • Xian-Qiang Chen
  • Nannan Xing
  • Bin Yang
  • Xuefeng Zhou
  • Chenghai Gao
  • Yong-Hong Liu
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


Two novel sequiterpenes isosuberosenol A (1), suberosain A (2), and a new pregnane derivative 4-hydroxymethyl-5β-pregnan-3, 20-dione (3) have been isolated from the South China Sea gorgonian Subergorgia suberosa. Their structure and relative stereochemistry were established based on the detailed spectroscopic analysis, including HR-ESI-MS, 1D- and 2D NMR spectra. The skeleton of isosuberosenol A (1) have been previously undescribed. The discovery of isosuberosenol A (1) provides some strong support for the plausible biogenetic pathway of quadrone type sesquiterpenes.

KEYWORDS
  • sesquiterpene
  • pregnane derivative
  • Subergorgia suberosa

SUPPORTING INFORMATION


Supporting Information
Download File A7-137-RNP-1904-1257-SI.pdf (2.6 MB)