JOURNAL 2332


Records of Natural Products
VOLUME & ISSUE
Year: 2022 Issue: 6 November-December
PAGES
p.515 - 537
STATISTICS
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AUTHORS
  • Dexia Wang
  • Xin Dong
  • Yanyan Nie
  • Wen-Ting Yang
  • Chengshou Li
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


GGenus Siegesbeckia has been utilized as herbal medicine for treating arthritis, stroke, rash and other diseases for hundreds of years in East Asia. Modern pharmacological researches demonstrated the species of genus Siegesbeckia contains numerous naturally occurring active compounds. Till now, 250 compounds have been separated from Siegesbeckia species, namely 128 diterpenoids, 71 sesquiterpenoids, 14 flavonoids and 37 other compounds. A number of studies showed Siegesbeckia extracts or constituents possessed various therapeutic activities, including anti-inflammation, analgesia, anti-cancer and so on. Some of them have a bright prospect in naturally occurring drug discovery.The information provided by this review is expected to be beneficial for further phytochemical and pharmacological studies of the genus Siegesbeckia.

KEYWORDS
  • Siegesbeckia
  • kirenol
  • diterpenoid
  • anti-inflammation
  • sesquitepenoid

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