Three Rare Furan Derivatives Transformed from Secoiridoids were Isolated from the Roots of Gentiana macrophylla

Short Report

JOURNAL 2333

Records of Natural Products

VOLUME & ISSUE

Year: 2022 Issue: 6 November-December

PAGES

p.651 - 656

DOI ADDRESS

http://doi.org/10.25135/rnp.322.2201.2333

STATISTICS

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AUTHORS

Wei Hu
Yihan He
Yangyang Yin
Ye Yang
Huanhuan Fu
Zhe Li
Zhenggang Yue

GRAPHICAL ABSTRACT

ABSTRACT

Abstract: Three furan derivatives (1-3) were isolated from the methanol extract of Gentiana macrophylla Pall. (Gentianaceae). Their structures were determined on the basis of spectroscopic analysis including HR-MS, 1D and 2D NMR. Genfurtate (1) was identified as a new compound, while, swertianglide (2) was firstly reported in genus Gentiana, and anglelone (3) was firstly reported in the plant G. Macrophylla. Accordingly, their biosynthesis pathways transformed from secologanin in G. macrophylla was deduced.

KEYWORDS

Gentiana macrophylla
Gentianaceae
furan derivatives
structural elucidation
biosynthesis
secoiridoid glycosides

SUPPORTING INFORMATION

Supporting Information

Download File A15-322-RNP-2201-2333-SI.pdf (850.72 KB)