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Chemical Constituents from the Roots of Rehmannia glutinosa

Original Article

JOURNAL 2625

Records of Natural Products
VOLUME & ISSUE
Year: 2023 Issue: 4 July-August
PAGES
p.615 - 621
DOI ADDRESS
http://doi.org/10.25135/rnp.380.2211.2625
STATISTICS
Viewed 3659 times.
AUTHORS
  • Penghua Shu
  • Shujing Cai
  • Xiaojian Zhao
  • Shuo Zang
  • Ruihua Li
  • Yabing Ge
  • Xiaoqing Lu
  • Xialan Wei
  • Yuan Yang
  • Haitang Yang
  • Na Sun
PDF OF ARTICLE

GRAPHICAL ABSTRACT

ABSTRACT

Ten secondary metabolites, including one new monoterpene rhamnoside (1), five terpenoids (2–6), two nucleosides (7–8), and two phenylethanoid glycosides (9–10) were isolated from the roots of Rehmannia glutinosa. Their structures were determined by spectroscopic analysis such as NMR and HR-ESI-MS. In the tyrosinase inhibitory assay, compounds 2, 6 and 8 showed inhibition against tyrosinase. Compounds 1, 4, 5, 6, 9 and 10 are being reported in the genus Rehmannia for the first time.

 KEYWORDS
  • Rehmannia glutinosa
  • rhamnoside
  • phenylethanoid glycoside
  • tyrosinase

SUPPORTING INFORMATION

Supporting Information
Download File A3-380-RNP-2211-2625-SI.pdf (1.95 MB)