JOURNAL 2832
Records of Natural Products
VOLUME & ISSUE
Year: 2023 Issue: 5 September-October
Year: 2023 Issue: 5 September-October
PAGES
p.947 - 951
p.947 - 951
STATISTICS
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Viewed 752 times.
GRAPHICAL ABSTRACT
ABSTRACT
In the current study, a new lignan (1), named callignan, as well as two known ones (2 and 3), were obtained from the EtOAc extract of the leaves of Callicarpa kwangtungensis. The structure elucidation of 1 was conducted by detailed interpretation of the 1D and 2D NMR spectroscopic data. Optical rotation of compound 1 and ECD data revealed that the compound was a racemic compound. Compounds 1-3 showed moderate effects with IC50 values of 46, 29, and 42 mM on NO production in LPS-induced RAW 264.7 cell inflammation model..
KEYWORDS- Callicarpa kwangtungensis
- callignan A
- neolignan
