JOURNAL 3430
Records of Natural Products
VOLUME & ISSUE
Year: 2025 Issue: 3 May-June
Year: 2025 Issue: 3 May-June
PAGES
p.239 - 246
p.239 - 246
STATISTICS
Viewed 1079 times.
Viewed 1079 times.
GRAPHICAL ABSTRACT
ABSTRACT
Two new diketopiperazine alkaloids, namely simplicamides A (1) and B (2), were isolated from the deep-soil derived fungus Penicillium simplicissimum GZWMJZ-1612. The structures of these two compounds were determined by NMR, HRESIMS, ECD calculation, and Marfey’s method. Compound 1 exhibited potent antioxidant capacity of ORAC and DPPH scavenging ability. Compound 2 displayed significant ORAC scavenging ability and α-glucosidase inhibitory activity.
KEYWORDS- deep-soil
- Penicillium simplicissimum
- diketopiperazine alkaloids
- antioxidant capacity
- α-glucosidase
