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Chemical Constituents and Pharmacology of Fomes fomentarius: A Systematic Review

Review Article

JOURNAL 3466

Records of Natural Products
VOLUME & ISSUE
Year: 2025 Issue: 4 July-August
PAGES
p.488 - 517
DOI ADDRESS
http://doi.org/10.25135/rnp.521.2503.3466
STATISTICS
Viewed 663 times.
AUTHORS
  • Chuanming Gong
  • Miaomiao Xu
  • Haonan Xu
  • Yuze Li
  • Chong Deng
  • Yi Jiang
  • Xiaomei Song
  • Dongdong Zhang
PDF OF ARTICLE

GRAPHICAL ABSTRACT

ABSTRACT

This paper mainly provides a systematic review of the chemical constituents and biological activities of Fomes fomentarius. As a widely distributed medicinal fungus, F. fomentarius has a long history of application in traditional medicine. Rich in chemical constituents, it contains over a hundred compounds such as steroids, triterpenes, and fatty acids. Pharmacological studies have demonstrated that this fungus exhibits multiple activities, including antitumor, immunomodulatory, antioxidant, antibacterial, anti-inflammatory and analgesic, antidiabetic, anti-hypoxic, and hepatoprotective effects. However, our current understanding of its action mechanisms and the synergistic effect among components remains limited. This review provides crucial references for further research and development of F. fomentarius.

 KEYWORDS
  • Fomes fomentarius
  • chemical constituents
  • pharmacological activities
  • Pyropolyporus fomentarius