JOURNAL 3430
Records of Natural Products
VOLUME & ISSUE
Available Online: April 27,2025
Available Online: April 27,2025
PAGES
p.1 - 8
p.1 - 8
DOI ADDRESS
http://doi.org/10.25135/rnp.510.2502.3430 (DOI number will be activated after the manuscript has been available in an issue.)
http://doi.org/10.25135/rnp.510.2502.3430 (DOI number will be activated after the manuscript has been available in an issue.)
STATISTICS
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Viewed 47 times.
GRAPHICAL ABSTRACT
ABSTRACT
Two new diketopiperazine alkaloids, namely simplicamides A (1) and B (2), were isolated from the deep-soil derived fungus Penicillium simplicissimum GZWMJZ-1612. The structures of these two compounds were determined by NMR, HRESIMS, ECD calculation, and Marfey’s method. Compound 1 exhibited potent antioxidant capacity of ORAC and DPPH scavenging ability. Compound 2 displayed significant ORAC scavenging ability and α-glucosidase inhibitory activity.
KEYWORDS- deep-soil
- Penicillium simplicissimum
- diketopiperazine alkaloids
- antioxidant capacity
- α-glucosidase
