Green chemical synthesis of α-hydroxyphosphonates

Original Article

JOURNAL 1705

Organic Communications

VOLUME & ISSUE

Year: 2012 Issue: 2 April-June

PAGES

p.50 - 57

STATISTICS

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AUTHORS

K. Suresh Kumar C. Bhupendra Reddy, M. Veera Narayana Reddy, C. Radha Rani, and C. Suresh Reddy

GRAPHICAL ABSTRACT

ABSTRACT

A green and efficient method for the preparation of α-hydroxyphosphonates (3a-n) in minutes of time with high yields is accomplished by grinding the mixture of various aldehydes (1a-n) and diethylphosphite (2) at room temperature under solvent free conditions in presence of piperazine as catalyst.

KEYWORDS

α-Hydroxyphosphonates
piperazine
grinding
diethylphosphite
green process.