Synthesis of benzyl chlorides and cycloveratrylene macrocycles using benzylic alcohols under homogeneous catalysis by HCl/dioxane

Original Article

JOURNAL 1712

Organic Communications

VOLUME & ISSUE

Year: 2012 Issue: 2 April-June

PAGES

p.58 - 63

STATISTICS

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AUTHORS

Yolanda Marina Vargas-Rodríguez, Melchor Vargas, René Miranda, Bernardo Francisco, Olivia Noguez, José Antonio Morales-Serna and Manuel Salmón

GRAPHICAL ABSTRACT

ABSTRACT

The synthesis of benzyl chlorides, cyclic derivatives cyclotriveratrylene and cyclotripiperotrylene were carried out in using the HCl/dioxane system as a catalyst. The reaction proceeded with high selectivity and is sensitive to the number of alkyl and methoxy substituent on the aromatic ring.

KEYWORDS

Benzyl alcohols
veratrole alcohol
benzyl chlorides
cyclotripiperotrylene
cyclotriveratrylene.