JOURNAL 651


Records of Natural Products
VOLUME & ISSUE
Year: 2013 Issue: 2 April-June
PAGES
p.129 - 132
STATISTICS
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AUTHORS
    Boonchoo Sritularak, Nopporn Boonplod, Vimolmas Lipipun and Kittisak Likhitwitayawuid Rec. Nat. Prod. (2013), 7:2 ; 129-132
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


A methanol extract prepared from the bark of Canarium subulatum Guillaumin (Burseraceae) showed significant anti-herpetic activity. Chemical investigation of this plant extract resulted in the isolation of nine compounds which included β -amyrin (1), (-)-cubebin (2), scopoletin (3), 3,4-dihydroxybenzoic acid (4), 3,3 ¢ -di-O-methylellagic acid-4 ¢ -O-α-L-rhamnopyranoside (5), 3,3 ¢ -di-O-methylellagic acid-4 ¢ -O-β-D-gluco-pyranoside (6), 3-O-methylellagic acid-4 ¢ -O-α-L-arabinofuranoside (7), scopolin (8) and 3-O-methylellagic acid-4 ¢ -O-β-D-xylopyranoside (9) . The structures of these compounds were determined mainly through analysis of 1H and 13C NMR and MS data. All of the isolates were evaluated for anti-herpetic and DPPH free radical scavenging properties. β -Amyrin (1) and ( - )-cubebin (2) showed moderate anti-herpetic activity, whereas 3,4-dihydroxybenzoic acid (4), 3,3 ¢ -di-O-methylellagic acid-4 ¢ -O-α-L-rhamnopyranoside (5) exhibited recognizable DPPH free radical scavenging potential. This study is the first report on the chemical and biological properties of C. subulatum.

KEYWORDS
  • Canarium subulatum
  • Ellagic acid glycosides
  • Burseraceae
  • Anti-herpetic activity
  • Free radical scavenging activity.

SUPPORTING INFORMATION


Supporting Information
Download File 19-RNP-1208-136-SP.pdf (39.12 KB)