JOURNAL 1505


Records of Natural Products
VOLUME & ISSUE
Year: 2020 Issue: 4 July-August
PAGES
p.292 - 296
STATISTICS
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AUTHORS
  • Amany Elsayed Ragab
  • Abdel-rahim Sayed Ibrahim
  • Francisco Léon
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


Minor metabolites of  Fusidic acid (1) using the fungus Cunninghamella echinulata NRRL 1382 were investigated for discovering previously unstudied reactions. An unprecedented fusidic acid derivative, C-27-hydroxy-3-O-formyl fusidic acid (2) was isolated, and its chemical structure was fully elucidated using various spectroscopic techniques including 1D, 2D NMR and HRESIMS. This is the first report for formylation reaction by C. echinulata.

KEYWORDS
  • Fusidic acid
  • Cunninghamella echinulata
  • 3-O-Formylation

SUPPORTING INFORMATION


Supporting Information
Download File A7-168-RNP-1912-1505-SI.pdf (732.17 KB)