Fusacintone A, a New Polyketide from the Endophytic Fungus Fusarium tricinctum from Fritillaria monantha

Short Report

JOURNAL 3464

Records of Natural Products

VOLUME & ISSUE

Year: 2025 Issue: 3 May-June

PAGES

p.302 - 306

DOI ADDRESS

http://doi.org/10.25135/rnp.514.2503.3464

STATISTICS

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AUTHORS

Qing Liu
Wei-jie Tian
Lei-lei He:
Zheng-hui Li
Bao-bao Shi

GRAPHICAL ABSTRACT

ABSTRACT

A previously undescribed polyketide (1) and four known compounds (2-5) isolated from the endophytic fungus Fusarium tricinctum from Fritillaria monantha. Compound 1 showed anti-inflammatory activity by inhibiting NO production with an IC50 value of 17.6±0.46 µM.

KEYWORDS

Fusarium tricinctum
endophytic fungus
polyketide
structural elucidation
anti-inflammatory

SUPPORTING INFORMATION

Supporting Information

Download File A9-514-RNP-2503-3464-SI.pdf (1.19 MB)