JOURNAL 3518
Records of Natural Products
VOLUME & ISSUE
Available Online: July 14,2025
Available Online: July 14,2025
PAGES
p.1 - 6
p.1 - 6
DOI ADDRESS
http://doi.org/10.25135/rnp.2505.3518 (DOI number will be activated after the manuscript has been available in an issue.)
http://doi.org/10.25135/rnp.2505.3518 (DOI number will be activated after the manuscript has been available in an issue.)
STATISTICS
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Viewed 59 times.
GRAPHICAL ABSTRACT
ABSTRACT
NNotopterygium incisum is widely used in clinical practice because of its complex chemical composition and remarkable pharmacological effects. In this study, a previously undescribed lignan (1) was isolated from N. incisum. Its structure was evaluated through examinations of the NMR, HREIMS data and ECD calculation. Compound 1 demonstrated significant anti-inflammatory potential by inhibiting the secretion of nitric oxide (NO) in lipopolysaccharide (LPS)-induced macrophages, with an IC50 value of 3.57 μM.
KEYWORDS- Notopterygium incisum
- lignan
- anti-inflammatory activity
