Chemical Composition and Biological Activity of Lomelosia rotata (M.Bieb.) Greuter & Burdet

This study aimed to determine the phenolic compositions and biological activities of Lomelosia rotata (M.Bieb.) Greuter & Burdet (Caprifoliaceae). According to HPLC/MS-MS analysis results, quinic acid (253.058 mg/g) was detected as the primary component in L. rotata methanol extract. The total phenolic and total flavonoid contents of the extract were examined using the Folin-Ciocalteu reagent and aluminum chloride colorimetric assays, respectively. Phosphomolybdenum, 2,2-diphenyl-1-picrylhydrazyl radical-scavenging (DPPH), ferric-ion-reducing power (FRAP), and cupric-ion-reducing antioxidant activity (CUPRAC) methods were used to evaluate the antioxidant capacity. L. rotata methanolic extract showed an effective DPPH scavenging activity (IC50 = 23.30 μg/mL). Results showed that the extract had moderate reducing activity toward cupric and ferric ions. The methanol extract showed no antibacterial effect. Our study suggests that L. rotata extract has potential use as a natural antioxidant for food preservation and human health.