JOURNAL 346


Records of Natural Products
VOLUME & ISSUE
Year: 2016 Issue: 1 January-February
PAGES
p.103 - 108
STATISTICS
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AUTHORS
    Zeyad Alresly, Ulrike Lindequist, Michael Lalk, Andrea Porzel, Norbert Arnold and Ludger A.Wessjohann
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


Phytochemical investigation of the ethyl acetate extract of the fruiting bodies from the basidiomycete Piptoporus betulinus led to the isolation of a new bioactive lanostane triterpene identified as 3 b -acetoxy-16-hydroxy-24-oxo-5α-lanosta-8- ene-21-oic acid (1). In addition, ten known triterpenes, polyporenic acid A (5), polyporenic acid C (4), three derivatives of polyporenic acid A (8, 10, 11), betulinic acid (3), betulin (2), ergosterol peroxide (6), 9,11-dehydroergosterol peroxide (7), and fomefficinic acid (9), were also isolated from the fungus. All isolated compounds were tested for antimicrobial activity against some Gram-positive and Gram-negative bacteria as well as against a fungal strain. The new triterpene and some of the other compounds showed antimicrobial activity against Gram-positive bacteria.

KEYWORDS
  • Piptoporus betulinus
  • triterpenoids
  • antibacterial activity
  • iceman “Ötzi”.

SUPPORTING INFORMATION


Supporting Information
Download File 12-RNP-1410-220-SI.pdf (587.29 KB)